Tools like CRISPR-Cas9 are creating new opportunities for innovation in St. Louis, as well as risks around IP protection and regulation.

UC and Broad have been involved in two interferences at the patent office. Interference No. 106,115 was the second interference between UC and Broad over patent rights to CRISPR-Cas9 technology in ...

A recent study utilizing cryo-EM advances our understanding of how bacterial immune systems function and reveals new aspects ...

The vitamin B2 (riboflavin) must be absorbed through diet: it can be found in dairy products, eggs, meat, and green vegetables. The body’s metabolism converts vitamin B2 into molecules that protect ...

The 10th Annual Smithies Symposium will take place on Thursday, March 26 from 3 to 4:30 p.m. (doors open at 2:30 p.m.) in the UNC Medical Biomolecular Research Building (MBRB), Room 2204, and is open ...

We performed both homology-based and GUIDE-seq nomination of candidate off-target sites, which resulted in the testing of 5002 sites from four healthy donors (not shown). We then nominated additional ...

Rapid advancements in CRISPR and next-generation gene editing technologies, combined with a strong clinical pipeline ...

Co‑injecting three common amino acids with LNPs dramatically boosted both mRNA delivery and CRISPR gene editing efficiency in preclinical models.

CHICAGO – A CRISPR-Cas9-based investigational therapy was linked with a drop in serum transthyretin (TTR) levels in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to ...