Mixed linear model (MLM) methods have proven useful in controlling for population structure and relatedness within genome-wide association studies. However, MLM-based methods can be computationally ...
Although genome-wide association studies (GWASs) have identified numerous loci associated with complex traits, imprecise modeling of the genetic relatedness within study samples may cause substantial ...
The generalized linear model (Nelder & Wedderburn, 1972) has become an elegant and practical option to classical least-squares linear model building. We consider the specific problem of generalized ...