Use of total body weight (TBW) in underweight and non-obese patients is widely accepted. Use of ideal body weight (IBW) for determining the mg/kg/dose may also be considered.

Patients who are in renal failure, receiving dialysis, or have unstable renal function or acute kidney injury should initially be dosed with one time doses of aminoglycosides, and therapeutic drug monitoring …

Monitoring of ototoxicity is recommended for prolonged duration of greater than 14 days. If it is clinically feasible and appropriate, monitor cochlear toxicity by audiometric function at baseline and during …

For gentamicin to be used safely, health care professionals must carefully monitor kidney function and check for symptoms of vestibulopathy (damage to the vestibular system).

Apr 10, 2023 · Gentamicin, like all aminoglycosides, exhibit concentration-dependent killing. Higher concentrations correlate with greater antimicrobial killing. For these reasons, clinicians should …

Policy for the administration and monitoring of once-daily gentamicin at Gloucestershire Hospitals NHS Foundation Trust (GHNHSFT). Gentamicin is the aminoglycoside of choice at GHNHSFT due to its …

Conventional/traditional dosing: Please consult pharmacy to help with dosing and monitoring plan. Below are suggested peak and trough goals based upon infection: ... Cystic fibrosis (CF) patients: …

Nov 22, 2024 · Dosing and monitoring of aminoglycosides in the treatment of mycobacterial infections, tularemia, plague, and brucella are discussed in the topics dedicated to those infections.

Aug 4, 2015 · Gentamicin can cause serious dose-related side effects including nephrotoxicity and irreversible hearing loss, so it is important to ensure patients receive the correct dose and are …

XII. Caveats about monitoring aminoglycoside concentrations A. Concentrations may be falsely elevated if the sample is drawn inappropriately. a) When the sample is drawn through the same line used to …